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H. Söderbäck, H. Mahteme, P. Hellman, and G. Sandblom
Published online: Front Surg.2016; 3: 28
DOI:  10.3389/fsurg.2016.00028

Abstract

Wound dehiscence and incisional hernia are potentially serious complications following abdominal surgery. Although prophylactic reinforcement with on-lay mesh has shown to reduce the risk, a permanent mesh carries the risk of seroma formation, infection, and persistent pain. The aim of this study was to assess the safety of a resorbable on-lay mesh to reinforce the midline suture in patients with high risk for wound dehiscence or incisional hernia.

Method
Sixteen patients with three or more risk factors for wound dehiscence or incisional hernia were included. A TIGR Matrix mesh, composed of a mixture of 40% copolymer fibers of polyglycolide, polylactide, and polytrimethylene carbonate and 60% copolymer fibers of polylactide and polytrimethylene carbonate, was placed on the aponeurosis with an overlap of five on either side and fixated with continuous monofilament polydioxanone suture. All postoperative complications were registered at clinical follow-up.

Results
Mean follow-up was 9 months. One patient developed a seroma that needed drainage and antibiotic treatment. One patient had a wound infection that needed antibiotic treatment. There was no complication requiring a reoperation. No wound dehiscence or incisional hernia was seen.

Conclusion
On-lay placement of TIGR Matrix is safe and may provide a feasible way of reinforcing the suture line in patients with high risk for postoperative wound dehiscence or incisional hernia.

Larger samples are required, however, to draw conclusions regarding the safety and effectiveness of this technique.